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Technology

Orbit Biomedical is developing surgical devices and procedures designed to deliver one-time therapies to the subretinal space. Our team brings years of expertise in biomedical engineering, medical device development and clinician training to ophthalmology. The current focus of our research efforts is on delivery to the subretinal space for the treatment of blinding eye diseases*.

The subretinal space

The retina is the thin layer of tissue which lines the inside of the back of the eye. The retina detects light coming in through the lens, and translates the light signals into neural signals to be sent to the brain.

The eye is regarded as an excellent target organ for one-time therapies due to its accessibility, small size, compartmentalization and relative immune privileged status. Placing therapeutics directly in the sub-retinal space, the space between the retinal pigment epithelium (RPE) and choroid layer, allows direct access to critical target tissues.

Access to the subretinal space requires vitrectomy and injection through the retinal tissue

The subretinal space has traditionally been accessed via an injection across the eye in conjunction with vitrectomy (removal of the vitreous, the gel-like substance that fills the eye).

Our goal is to access to the subretinal space without vitrectomy and without the need to pierce the retina

Orbit Biomedical is developing a device and procedure with the goal of enabling the subretinal space to be accessed without removal of the vitreous, and without the need to make a hole in the retina. Our key focus is on the safety, accuracy and consistency of delivery.

Collaboration with expert surgeon faculty

In addition to focusing on safety, accuracy and consistency, our biomedical engineers continue to work with expert surgeon faculty to streamline the user interface and make our platform as simple and easy to use as possible.  Orbit Biomedical’s team has significant expertise in

– Human factors engineering
– Surgical procedure development
– Surgical instrumentation development
– Surgical visualization tools
– Microfluidics and Catheter technologies

* Our technology is under development and our device is currently not approved for sale in any country.